A isolated d-pawn(or queen pawn) that can often be found in the Queen's gambit and many other openings. If used properly, it can be very powerful.
For more on this subject check out the book "Winning Pawn Structures" by Alexander Baburin. He explains the isolani in depth. He emphasizes how to best iniate an attack when you have the isolani, and what to watch out for when playing against it!
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