Yes, the sicilian defense is blacks best chance to win against 1.e4, statistically. However, at our level (<2000) its best just to stick to the openings that we first learn because a lot of moves are mistakes. If you want to learn an agressive opening for fun then I do reccomend looking at the open sicilian. It is by far my favourite opening especially in the najdorf where white castles queen side. I have had many games where I am at the edge of my seat and eyes glued to the screen because of all the attacking chances from both sides. When you win its all the better from all the tension. Players like Fischer and Kasparov have played beautiful games with the najdorf.
Good luck if you choose to play the sicilian!!
What openings do you know in which black fights for the advantage, not for boring equality? I want something very aggressive, but not things like Latvian Gambit, which are unsound. Is Sicilian really black's best chance for the win against 1.e4?