Study The Queen's Gambit!
Because this group is named the 10,000 Queen's Gambit Players, I have noticed that we should study the Queen's Gambit, which appears after the following moves:
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After that, it could branch off into the following variations:
2... dxc4 QGA (Queen's Gambit Accepted) usually followed by 3. e4, though 3. e3 and 3. Nf3 are also seen.
2... e6 QGD (Queen's Gambit Declined) Black refuses to take this pawn but blocks in his c8-bishop. Usually followed by 3. Nc3, though 3. Nf3 is also seen.
2... c6 Slav Defense Black also refuses to take the en prise pawn, though the b8-knight can't jump to c6 and place pressure on the d4-pawn. Usually followed by 3. Nc3 or 3. Nf3.
2... Nc6 Chigorin System Black again refuses to take, but counterattacks the d4-pawn. This is not usually good because it's bad to block your c-pawn in Queen Pawn Games; starting with 1. d4. It can be followed by 3. cxd5 or 3. Nc3.
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Rarely ever seen systems of the Queen's Gambit; these are played only by beginners.
2... Nf6 (Marshall Defense) Black prepares for quick development, though this blocks a space-gaining manuever of the f-pawn.
2... Bf5 (Baltic Defense) Black unexpectedly stops following regular opening theory.
2... g6 (Alekhine Variation) Black prepares to place pressure on the center by 3... Bg7. However, the pawn is perfectly rigid after it gets a lot of defense.
2... c5 (Symmetrical Variation) It looks like it forces a trade; though he can lose ability to castle but develop a piece.
2... e5 (Albin Counter Gambit) Black sacrifices a pawn for a lead in development and/or more space, though white can play "takeback" on the space. Followed by 3. dxe5 d4.
Those are the lines of the Queen's Gambit. Hope you start using them!