I guess the worst high level blunder of all time is Kramnik (who even was World Champion at that time) being on the receiving end of a mate in 1 (yes, you read that right: one!) that he simply managed to overlook. With classical time controls.
You still can easily google it, here's one example article about it:
http://en.chessbase.com/post/how-could-kramnik-overlook-the-mate-
As far as I'm aware no other Chess World Champion embarrassed himself that way. Ever.
 
     
     
     
      
It would be interesting to get acquainted with GM's blunders. That would make me feel a little better..
What do you guys think?