Against the Nimzowitsch defense, the Queens gambit is a given.
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It depends on accepted or declined, Queens Gammbit easily can be diverted to a center game of exchange. d4 NF6. c4 e6. NF3 b6. counter/NC3 (4. a3 bB7 5. Nc3) 4...Be7 8.Williard_Sarmiento. Check it out!
I use the Queens Gambit quite often, and the literature and commentaries i've read all figurativly refer to accepted v declined, Ah thats where experince alone will propogate your set-up, as end game is usualy a constant here.