You mean like the Philidor or something? 1. e4 e5 2. Nf3 d6.
There are plenty of response to 1. e4 besides the Sicilian and the Petrov. I am not even sure if you are aware of 1. e4 e5 2. Nf3 Nc6. There are ussually 3 or 4 Spanish games from every high level tournament and the Caro-Kan is not outlandish either.
A few weeks ago, i asked was there a solid and lesser known response for white against the Sicilian and several said c3 - and that was fantastic!
Now, in response to White's 1.e4 2.Nf3 besides the Sicilian or fianchetto on Black's king side or some variation of that and/or Dragon and besides Petrov's Defense which seems good but some might say a bit boring, and besides
1 ...e5 2.Nf3 ? and going into some kind of 2 N's or 3 N's or 4 N's game, is there a solid and lesser known response/defense for Black?
Thanks for any suggestions.