If your opponent plays 1...c5 then you are in for a steel cage death match type of game from the very start. If that is not the type of game you want, then don't play 1 e4.
But White has very good chances against the Sicilian. If you like to go for all out attacks, look at some games where Tal or Keres or Spassky destroys Black; if you are a positional player look at how Karpov used to crush the Sicilian.
If you like to start more slowly then the Alapin is a great choice.
The Smith Morra is great fun but I think if Black knows what s/he is doing, your chances will not be as good as the main lines.
The other system you might want to check out is the one where White plays an early Bb5. Having played both sides I would say that it is easier to find a plan for White than for Black in those kinds of positions.
personally i feel that there is a lot of fuss about nothing regarding the sicilian defence. Just play grand prix attack or sensible normal developing moves.