It's a difficult question to answer because irregular can be fairly subjective.
Likely things such as 1.g4 are going to come to mind when you say ''irregular'', and as such most of the responses will urge you simply to develop in classical fashion and be ok.
However, as these threads often pan out, I find a lot of players authoring these posts will conider an ''irregular opening'' to be some offbeat gambit they've encountered which is actually fairly sound and requires concrete play.
For this reason you should try and attach some diagrams with examples of the types of openings you have trouble against.
I've found that my middlegame is quite solid, but I am often subjected to bad positions due to irregular openings surprising me. Does anyone have any suggestions on how to deal with this problem?