Practical Value in Openings

The great Magician from Riga once said: "There are two kinds of sacrifices: sound ones, and mine." Unfortunately, there hasn't been anyone to say: "There are two kinds of openings: explored ones and mine." It could be as grandiose as a completely different take on an opening to a slight change in moves that produces a fresh look in a position, right?

But where does it end? We all know about the plus and minus evaluations that computers give, the theoretical complexities that draw out to thirty moves or more, the off-beat paths, and the slightly more thrashed ones that don't promise an advantage, at least at the analysis board. At what point in rating levels does a practically-valued opening drop in value against a theoretical monster?

It doesn't have to be something like the Englund Gambit where tricky lines are pitfalls for people to drop a point. It might simply be preference or greater handling of the positions you know - but where does it end? Do you follow long theoretical lines, or even just jump into well-known positions, or do you play on the board where things are very different from analysis?

TL;DR: Post your practically valued openings. Beat 'em up at the board!

This  one is kinda useful in Bullet chess situations:

A00: Barnes Opening: Hammerschlag