What do I play against the Nimzo-Indian
You can try Qc2 but it passive and leaves black to do what he wants.
ok ill try Qb3 first
there are many many ways for both white and black to play in the nimzo. if you want to go a little offbeat and avoid mainlines you could try the romanishin variation 4. g3. moiseenko plays it a lot if you want someones games to check out.
The Nimzo Indian is one of the most correct defences for black. There is no sure way to get an advantage.
Qb3 leads to an equal position in a rather easy way. The most challanging options are Qc2 and e3 systems
there are many many ways for both white and black to play in the nimzo. if you want to go a little offbeat and avoid mainlines you could try the romanishin variation 4. g3. moiseenko plays it a lot if you want someones games to check out.
Ok ill try it
The Nimzo Indian is one of the most correct defences for black. There is no sure way to get an advantage.
Qb3 leads to an equal position in a rather easy way. The most challanging options are Qc2 and e3 systems
What do u mean by challenging?

I think when he says challenging it means that they are systems with which white can genuinely try for an opening advantage. As in the most challenging for black to equalise against.

I play the Nimzo-Indian as black and I will tell you it is astounding how flexible it is. my advice is avoid the Nimzo by not playing Nc3 untill you have castled, removing the opportunity to play the Nimzo, and forcing black to play the queen's Indian defense, which is solid but doesn't have a lot of the advantages of the Nimzo (e.g. pin on the knigt, white's potentially doubled c-pawns, etc.) the QID is a sister opening to the Nimzo Indian but is a little more rigid and less flexible because black must play b6 and Bb7, to establish the grip on e4 that the pin in the Nimzo normally provides.
I think when he says challenging it means that they are systems with which white can genuinely try for an opening advantage. As in the most challenging for black to equalise against.
OHHHHH ok now i get it now. Thank you :)
Qc2 instead of Qb3: d3 is the square on which your lightsquare bishop wants to be. I don't actually see how it is 'passive', since often in the nimzo indian or sometimes the queen's gambit declined lines the queen comes to c2 and lines up with the bishop against the kingside. Any professional game in which I've seen this or a similar position, Qb3 is not played. (It is entirely possible but I have not yet seen that)
You could play e3, g3, Nf3, Qc2, just a few of the most common

Yeah Qc2 is the Classical or "Capablonka" Variation. If you're gonna play the Nimzo as white, this is my recommendation just watch out for an early ...d5 by black as this leads to a very messy situation, and both of white's center pawns come under attack, the c4 pawn directly, and the d4 pawn is left exposed and under defended when the smoke clears