To the OP:
What about this game? Oh, well that was just some 2550 who was over matched against Luke McShane. Perhaps this one? Wait, but that was an endgame, so Shirov probably made a mistake somewhere. Ivanchuk - Ponomariov 2011, 0-1 in 26 moves.
You say "White is statistically outscoring Black quite heavily," and this may be true, but it's also true of any other opening. As a number of books proclaim, Black is OK.
I've been reading more and more on the Ruy Lopez, and I'm absolutely convinced that it is a fantastic opening (that is not to say that I am good enough to make many valid criticisms on openings in the first place--- but that's not the point!).. what I mean is, that it is clearly an opening that can cause tremendous amounts of pressure, and that really seems to favor the white player.
The question I've been asking myself again and again is quite simply why? Why would Black ever allow the Ruy Lopez? This is what I don't understand! Even at the highest level, White is statistically outscoring Black quite heavily. And well, for someone who isn't a professional chess player it would be even more hopeless to try to fight the ruy lopez as black!
On the other hand, I have noticed that after 1.e4 e5 2.Nc3 - going down the old Spanish road is probably one of the best things to do for Black, relatively. I would suppose that the easiest way to not be destroyed is of course to hit e4 with c5.
note: of course, much of this goes to generalizations, but let's remember that discussions usually tread along that line anyway.