No, I've had both 10 and 11 and I do not think there are many changes. except for the graphics of course. If you want to analyze you should get rybka.
http://www.youtube.com/watch?v=s9-t5bPJuWc check this video.
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Doesn't Rybka using the same GUI though, which would give simlar output from analysis?
I currently have Chessmaster 9000. Is it worth it to upgrade to the new one for analysis purposes? I also have Fritz 8, but I don't find Fritz's analysis helpful.