Hippo and King's Indian do well against engines. The goal is to shut down everything and prevent pawn breaks and opening of the position.
anti-computer openings
You run into tactical difficulties playing against stockfish? You dont say? I beat stockfish almost every time! Except one time where I stalemated stockfish while trying to checkmate with a queen. What a shame.
Hippopotamus Defense seems obvious to me after that it depends of the algorithm or how is the artificial intelligence of the chess program made.
In any case a strong bot is above all a super calculator which has a strong memory (it notably knows an opening encyclopedia and this reminds of its games)