Moonnie, but Yusupov advises to switch to the Petroff ( 1. e4 e5 2. Nf3 Nf6 ) in his series.
He does not, he says that if you already have an opening you're happy with, then it's fine to stick to that. Yusupov's chapter on the Petroff (and on other openings) are more an example of how to study the opening in general, as well as a short primer on some Petroff lines.
The openings don't help much in the middlegame. The whole familiarity argument can only hold for so long because soon tactics and other considerations will force a change in the game. And then there is the chance that the opening goes in a direction you've never encountered.
True in a sense, it just depends on how well someone may have studied the variations to their preferred opening.