Do you play the Najdorf against the Open Sicilian?
If not, 2...a6 is a waste. Only Najdorf players should play 2...d6 or 2...a6, and the first is better than the second.
The only problem with 2...d6 is that White can get the Grand Prix Attack with having to deal with the aggressive lines with an early ...d5. 2...d6 is not "bad" or "dubious".
The problem with 2...a6 is that in the Closed Sicilian, Black usually looks to expand on the Queenside with ...b7-b5, ...b5-b4, and ...a7-a5. By going to a6, you waste a move on your Queenside expansion. Usually it is assisted by a rook on b8 rather than a pawn on a6 to advance the b-pawn.
If you are a Kan player, play 2...e6.
If you play anything else (Dragon, Classical, Taimanov, etc), play 2...Nc6 against 2.Nc3.
The reason a Najdorf or Kan player should not play 2...Nc6 is because after 3.Nf3, intending 4.d4, what do you do? You cannot play a Kan or Najdorf any more due to ...Nc6. You can still get a Taimanov, Dragon, etc.
Tonight, I'm playing over-the-board, where, based on the pairings, it's likely I'll have Black in a game that begins 1. e4 c5 2. Nc3, at which point I'd like to try 2. ... a6 with a quick ... b5. If prior games are anything to go by, my opponent is likely to play a standard closed Sicilian setup, with g3, Bg2, d3, Nge2, f4, etc.
I've been looking at some lines and reading a brief account of this line in a book (Georgiev, the Sharpest Sicilian), but would be welcome for any further pointers on how to play this, or any instructive games I would profit from studying, videos on the line, etc.