I am both e4 and nf3 player, so
As nf3, i HATE the black mustang. That’s all
As e4, french is a pain in the aas, cuz i never prepare the wing gambit properly(ironic)
Alekhine and nimzowitsch, cuz i never know what to do against them.
As black, london system, exchange french, both Nc3 and Nd2 french(cuz i play the blackburne).
Exchange caro kann with Bd3 and h3, advanced en passant caro kann, alapin sicilian, declined lisbon gambit against the london
the love fest's over! what are those openings and lines that you hate facing, or even having to play?
I hate facing almost EVERYTHING as black except 1.d4 now because I've finally found MY current favorite
englund hartlaub/charlick gambit 
hate having to "slav-wall"
hate the toothless marshall scandinavian
despite an actual winning record
I REALLY hate the french
after all the pummeling I took facing it as a 1400, and even now after over a decade of trying to find a working gambit (FORGET monte carlo! black won't allow it!) it IS so delicious crushing black in under 20, when I do in the alapin diemer gambit
, but I still have a slightly losing record with even that
I can't stand trench weasel hypermoderns pirc, modern & owens

what lines drive you nuts?