I've started playing 1.b3 and the positions you get are generally pretty simple, with a couple of exceptions. It also allows you to avoid, or favourably meet, some prepared 'systems' people like to play against everything non e4, such as the KID and dutch.
Playing 1..b6 as black would create a very simple repertoire, although admittedly the positions you generally get are not exactly that appealing, the database shows very few strong players except Nakamura using it.
@Robert0905: That looks like the KIA. Yes, I have tried it and it saves a lot of time memorizing. I like it. I just can't get Black to keep his pieces still while I develop.