The Modern is probably the closest thing to a universal Black Defense. It shows up occaisionally in top level play. World Champion Magnus Carlsen played it recently, though he lost after saccing a Bishop for two pawns.
http://tiger.bagofcats.net/chess/carlsen-plays-the-modern-again/
The Dark Knight System is interesting. It advocates playing Nc6 in reply to anything White does. It often leads to variations of The Pirc. It's offbeat, but not wildly so. The late GM Tony Miles used to play 1 ... Nc6 a lot.
http://kenilworthian.blogspot.com/2013/04/the-dark-knight-system-review.html
There's also The Lion (aka. called The Black Lion), which is really sort of a Philidor, but interesting.
http://www.vanrekom.nl/thelion/indexgb.htm
Something you can play everygame...
edit:that title was dumb...