What is the best variation for the Sicilian?

I've done well over the years with the O'Kelly (2...a6), and still play it occasionally. The point is that if White plays 3.d4, Black can get a good game:

Black has an active position and often gets in an early d5, with equality. Clued-up White players play 3.c3, 3.Nc3 or 3.c4 instead, but none of these is a refutation, and Black can learn ways of dealing with them.

I almost always play the Sicilian as black. However, it took several months and a lot of losing to learn it. I kept losing to variations of the Yugoslav attack. If you're going to play the Sicilian, then you will need to know how to counter that. I have noticed that it's a lot easier to play the Sicilian on chess.com because players here don't seem to play the Yugoslav. That's probably just because of the level of players I play, though.

The Kan is very solid and good for beginners. A big advantage is that there is very little theory.

This is how you should counter the Yugoslav.

Thanks, that's pretty useful.

BTW when they play h4 play h5

I think:

the delayed alapine 

“... A question about my favorite is by far my least favorite ...” - CGP Grey

My first 1.e4 defense was the Dragon. I saw it in a Chess Life magazine, and I thought that with a name like that it must be cool. I played it for years with great results against up to USCF “A” players. I gave it up after getting tired of facing huge kingside attacks, and also because more and more books started coming out (this was 30+ years ago) showing White exactly how to play the kingside attack. Suddenly players 400 points lower were playing GM moves against me. It was a lot less fun after that. I agree with others that the Kan and Taimanov are good choices, simpler than the Najdorf and Dragon, and requiring less memorization. Don’t be afraid to try other openings, too. Just remember that learning new openings is often a slow and painful process. It takes experience with it to play an opening well, and you’ll lose a lot as you are learning. You have to take those losses, learn from them, and try again.

I gave up the Dragon when I taught a young man in juvenile detention how to play the Yugoslav Attack, then he just destroyed the Dragon anytime I let it out of its lair. "Sac, sac, mate," I believe is how Fischer put it. The kid had talent, but he got a prison sentence as an adult.

If you'd taught him the Najdorf instead, he might still be a free man.

I switched to the Najdorf, after a foray into the Taimanov. I like it.

I'm sure you've seen my Najdorf game. Things that live under rocks have seen it.

This is how you play against the Yugoslav