I don't typically unless I am desperate to play something different against a player I have played 20+ times.
I also avoid the Grunfeld like the plague though. French and King's Indian Defenses for me! Occasionally I will play a Sicilian via 1.e4 e6 2.Nf3 c5 (instead of d5), and occasionally I'll play a Dutch (1.d4 e6 2.c4 f5, where if say, 3.g3 Nf6 4.Bg2 c6 5.Nf3, then I will play 5...d5, but I wouldn't call that the same as 1.d4 d5 by any stretch of the imagination.
So not the same main defenses as you (French vs Sicilian and King's Indian vs Grunfeld), but like you, not e4 e5 or d4 d5.
After e4 e5? Or d4 d5? I haven't played e4 e5 and d4 d5 for decades. I did as a beginner and when I learned about openings, never played them again except against young beginners. I became devoted to Sicilian and Gruenfeld Defense. I played other defence ofc like Scandinavian, Carokann, French and Nimzo Indian and Queen Indian Defence. Anyone no longer play double pawn defence?/