C5
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- the move by black that defines the Sicilian Defense after 1.e4
- an important pawn-break in E4 openings such as the French Defense and Caro-Kann Defense.
- an important pawn-break in D4 openings like the Tarrasch Defense to the Queens gambit
- An active developing square for black's queen bishop in opennings like the Italian Game and Classical Ruy.
- a strong post for black's queen knight in many openings.
- The move defining the Symmetrical English after 1.c4?!
- If white conducts a minority attack via b2-4-5, attacking the c6 pawn, an option for black is to advance the pawn to c5.
- I got nothing else, do you?