Stockfish does not pick the move for you OTB (otherwise you are basically... a cheater). Grandmasters use engine for preparation. So what? It requires more accuracy from both sides and GM nowadays still perform amazing games.
And unless your opponent is a monkey, you still have to play well when using a opening system. Thinking that systems do not require understanding and knowledge to be properly handled is a common mistake from those who know ANYthing about them.
It's also a common mistake from weaklings who pick systems without any proper work.
Main line ('cause yes, there are sidelines) of the Nimzo-Larsen?
Positional themes such as: Control over the e5 square, giving up the bishops pair but keeping the center close (with thematic good knight against bad bishop if we reach an endgame) / play against double pawns, outpost in c4 / huge tactical shot on Black easy mistakes.
Colle / Nimzolarsen / Zukertort... Those systems where extensively used by masters of the past without any dogmatic "bahbahbah c4 pawn bahbahbah!" in brilliant games. And to win, not to sleep on the board.
There is no shame in trying to play like Zukertort, Nimzovitch, Lasker, Rubinstein, Petrosian, Polugaevski, Tal, Fischer and so forth. Maybe it does not always match today styles but it's still chess, and within good hands it can be great chess.
Today's proof: victory of Carlsen over Giri, around 2800 elo points.
At 2800, it's bad faith if you say "it's not chess". Okay, let's say Giri had a flue that brought him to patzer level, sure.
[eyerolling]
Most London players I know like closed centers and wing manoeuvers (the ones they crave for in their mainline).
So I came up with something to blow up the center which is kind of "Nope" to the London:
An idea like another. I think you can also reach it when you are a 1...d5 player.
PS: I'm definitely not a London player, I'm not the one moaning here and that's exactly because you are that I (respectfully) say that your attitude against them is ridiculous. ;)
This is actually similar to what I do, except I push d5 much sooner.