Funny you should post this!
I just this minute lost a game against a guy rated 500 points higher than me.
I used it as a chance to try out a new opening(Slav/Semi-Slav)
I think I played pretty well up until about move twenty, then I gave up defending to snatch a pawn because I'd underestimated his counterattack and I was beaten fairly quickly after that.
I didn't really consider the rating difference other than to use the analysis board a LOT more than I would normally!
After the game I felt like I'd probably missed some defenses and was quickly onto computer analysis.
I'll try to post the game if you want.
Say you're playing someone related 500 or more points higher than you.
What are your goals? How do you feel after/during the game?
Do you go in expecting to lose and possibly learn something?
Do you hope to prolong the game as long as possible as opposed to being checkmated in the first 15 moves?
Do you do anything differently when playing a much higher rated player than you would if you were playing someone rated at your level or much lower?