you can.
a better question is:
Am I a good enough player to be 2 pawns down from the very beginning of the game just to avoid the open Sicilian?
if the answer is yes, then go for it and know everything one can know about the Smith morra gambit.
if the answer is no, or I'm not sure, then maybe the closed Sicilian or the Alipan is for you.
the other option is to just face the open Sicilian. if you play 1.e4, you can not avoid the Sicilian. you will play one of these choices. good luck👍.
As a reply to sicillian?