If you feel like you should, yes.
Should you resign if you only have ten seconds in bullet and your opponent has lots more?

I don’t play bullet games a lot, but if your opponent has 20 seconds left, say, and if you only had 10, then should you resign if the pressure is too much?
Nope. Sometimes you may get lucky and end up winning.

If he has 25 you must play on but not 20 sec. Blitz games damage your nerves if you play more than a warm up seson of 15 minutes
I don’t play bullet games a lot, but if your opponent has 20 seconds left, say, and if you only had 10, then should you resign if the pressure is too much?