Probably the two main questions I ask are:
1) Is this move stupid?
This can mean a lot of things from tactical blunder to strategic mistake... sometimes simple moves that do no harm to your position are best. It's also asking yourself something like, do I wish this move is good, or do I really believe it's good. It also has elements of trying to understand the candidate move in terms of your opponent's plans and possible moves. Am I playing this move because I'm afraid of my opponent doing something? Should I actually be afraid of that? If I change my move order can I deal with that later or do I have to stop my opponent right now?
2) What's the alternative?
Find at least one other reasonable candidate move, and compare the two to see which you like more.
I always seem to calculate a move or a line and then sometimes I forget about a certain diagonal or piece etc. What should I ask myself whenever I am thinking of a move. Like a mental checklist.