Against E4 I play French Defense or Nimzovitch Def. Against D4 I like The Classical Dutch, Kings Indian, or The Two Knights Tango.
which is the best response against d4 and e4
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f6
Dec 1, 2017
0
#6
It is the opinion of most higher ranked players that THE strongest replies to e4 and d4 are the Sicilian Najdorf and Nimzo-Indian Defense. These openings suit certain people. The best openings for you to choose are the ones that fit well with your playing style and ones you feel comfortable with. Someone who feels uncomfortable playing the Sicilian Najdorf may find it a joy to play the French Defense, etc.
i play sicilian najdorf about 50 games in tournaument
TINSTAABO
"There is no such thing as a 'best opening.' Each player should choose an opening that attracts him. Some players are looking for a gambit as White, others for Black gambits. Many players that are starting out (or have bad memories) want to avoid mainstream systems, others want dynamic openings, and others want calm positional pathways. It’s all about personal taste and personal need.
For example, if you feel you’re poor at tactics you can choose a quiet positional opening (trying to hide from your weakness and just play chess), or seek more dynamic openings that engender lots of tactics and sacrifices (this might lead to more losses but, over time, will improve your tactical skills and make you stronger)." - IM Jeremy Silman (January 28, 2016)
https://www.chess.com/article/view/opening-questions-and-a-dream-mate
The November 2017 issue of Chess lists the top twenty openings compiled from a list of 2402 September games where both players were rated over 2400 Elo. One can not take position on this list too seriously because it is greatly influenced by how the openings are grouped. For example, all the Retis are grouped together, while English is separated into 1...c5, 1...e5, etc. Nevertheless, for what it is worth, some of the list entries are: 126 Retis, 100 King's Indians, 97 Nimzo-Indians, 84 Caro-Kanns, 76 declined Queen's Gambits, 73 Slavs, 63 Catalans, 61 Najdorf Sicilians, 58 1...c5 Englishes, 55 Berlin Lopezes, 55 Queen's Indians, 49 Guioco Pianos, 48 1...e5 Englishes, 45 Kan Sicilians, 43 1...Nf6 Englishes, and 42 Taimanov Sicilians.
to answer your question you just have to consult a good database and see which openings score best on the top level - which are the sicilian against e4, and the nimzo indian against d4. HOWEVER, that doesn't necessarily mean that you also should play the nimzo, as you are no grandmaster and it also might not suit your style. There are many many openings that are completely playable and you should just go with the ones you like best.
My personal favourites are Sicilian dragon against e4 and Leningrad Dutch against d4
I think it's Sicilian defence