Thanks (brandonQDSH), that post gave me lot's to think about.
Had a question/query to this comment "Well if you have prepared responses to 1. e4 and 1. d4 and feel reasonably comfortable, then that's enough".
I think I know what you mean regarding 1. e4 (there are choices like silician, french, caro-kann, scandinavian, ...). But not sure about 1. d4.
Against 1. d4 someone would need to have a response against the queens gambit. But there are other 1. d4 openings (like Torre Attack, London System, Colle System, Veresov Opening, Blackmar-Diemer Gambit, Trompowsky, ...). So the question is how to get a handle on those. It would be nice for Black to have a 'system' he could use against all those (maybe not cutting edge - but something similiar and reasonably effective to use against each). I guess what i'm saying (asking), is that it seems that the response to the queens gambit might not be usable against all the other 1.d4 continuations by white.?. Can you give me your thoughts on this?
Well if you have prepared responses to 1. e4 and 1. d4 and feel reasonably comfortable, then that's enough. These are the only two openings that really punish opponent's for responding incorrectly, namely the Queen's Gambit. But with perfect play by Black, the drawbacks to any opening are minor.
You don't really need a set response to anything other than 1. e4 and 1. d4 because they are all rather passive. This is not to say that they are weak openings, but since they don't directly occupy the center, Black is left free to do a lot of things.
c4, f4, Nf3, and Nc3 present Black with lots of options. b3 and g3 offer Black even more choices. Random stuff like a4, h4, etc. is sort of like handing Black the tempo, which is fine since White starts out ahead anyway.
To use a practical example, let's say you're playing a game and someone opens 1. Nf3. If you want to play a 1. e4 style opening, you can transpose the game into a Guioco Piano, Ruy Lopez, etc. by countering Nc6. Your opponent will probably play something like 2. e4, unless he wants to do something offbeat like King's Indian. If you're feeling more comfortable with a 1. d4 opening on that day, you can counter with Nf6 (the mirror) or d5 and your opponent will probably opt to transpose into Queen's Gambit, which will allow you to play whatever you normally do against it.
1. e4 forces you to play a specific style of game, and 1. d4 does as well. But all the other openings give you the choice of being classical or hypermodern, and you can take the initiative in transposing the opening into something you're more comfortable with.