Short of expert level (2000+), you can probably play pretty much any opening, as long as it's not unsound, and be fine. .
Yes, and here lies the devil in the detail again. »as long as it's not unsound« you wrote. And how to decide if it's sound or unsound? Only by knowing opening theory .
@Spielkalb, principles and theory definitely seem similar, but theory is about specific lines and variations.
Principles are more generic, and mostly about learning how to properly develop, rather than about learning correct lines.
An example of learning opening principles would be:
"Which of the following is a better first move for white?"
or
And then:
"Which is a better second move for white?"
or
Etc... These are examples of opening principles (developing toward the center, attacking or defending central pawns, stuff like that...).
Principles and theory do overlap, but principles are less about learning correct variations, and more about learning the fundamentals of opening play.
Without properly learning opening principles, beginners might play like this, and not understand what they're doing wrong: