I really like e5.Game becomes more tactical and you dont need you know lot of theory like sicilian!
I play e5 and these defenses againt these opennings:!
king' gambit => falkbeer counter gambit
danish gambit =>d5 line
ruy lopez => berlin defense or sometimes janisch gambit
Italian game(Bc4) => two knight defense ulvestad variation
of course you should know how to play against scotch game and scotch gambit(pretty easy)
I had great succsuus with this repertoire
1...e5