Both are equally winning -- I would simplify in a heartbeat to eliminate any potential issues that might arise from my own mistakes. a5 may be the object best move, but I'd have a much easier time converting the win after Qxd4. This is probably a good poor example of a very "human-like" move in a position where there is also a competing, and superior, "engine-like" move.
[J'adoube: I guess it's hardly a good differentiator if the "engine-like" move is also obvious to many humans...]
OK, so you have the following (hypothetical) situation, you are clearly winning, but your opponent is playing on, as is his constitutional right.
Do you play the best move a5, or just Qxd4, removing all hope for a swindle?
I actually found that the second choice often leads to immediate resignation, thus a quicker win.