Here's an example from an endgame:
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Here's an example from one of my games. White's winning edge came from making sure black's knight on a5 remained useless all game long. As a result, white was effectively playing a piece up on the kingside. The knight didn't get free until white already had a winning combination.
BTW, this whole line with Na5 is theory. Black willingly accepts a bad knight in order to get queenside activity, and the theoretical debate is all about whether white can neutralize the activity while keeping black's knight terrible.