Yeah, SCID vs PC is great. You can download games from TWIC and have an updated database whenever you feel like.
Chessbase is commercial software.
That's a useful feature that was part of CB 11 when I bought it, but ceased being so about two years ago. Certainly a reason to consider SCID vs PC!
I actually found Chessbase and Fritz very clumsy to work with.
After using CB 8 and XP for several years, I found CB 11 and W7 clumsy at first. I'm more accustomed to it now. Preferences often seem driven by familiarity.
A detailed comparison of CB, SCID, and SCID vs PC could be useful. Maybe Chess Assistant should be included too. Is anyone familiar with all of these?