he was absolutely familiar with the opening (QGD Taratakower). For some odd reason he did not apply a very strong move shown to him by his seconds just months before the game... and the rest is history.
In fact Spassky had some great statistic too like he hadn't lost a QGD Tartakower in 10 year or something like this. Spassky would have been 100% comfortable, but yes, he played an inaccuracy in the opening.

Yeah Bobby Fischer always ALWAYS played e4....that is why Spassky was sooo surprised in game 6 when he played d4. Spassky was totally taken aback psychologically and Fischer played a brilliant game.
It was here when Fischer realized that chess was quickly becoming ALL about preparation. It bothered him greatly.
Ummm... Fisher did NOT play 1.d4 in game 6.
Spassky was not surprised, or something in that game- he was absolutely familiar with the opening (QGD Taratakower). For some odd reason he did not apply a very strong move shown to him by his seconds just months before the game... and the rest is history.