316 points of winning advantage is the checkmate.
What is the biggest material advantage you ever had

Bobby Fischer continued to play on against Spassky in game 11 of their match for the World Championship even after he had lost his Queen.
It was gruesome to watch. Recall that at the time of the match, Spassky was still World Champion. Who plays on a Queen down against the Chess Champion of the World?
Fischer does.
My highest material was 32