There really is no opening with the most "book moves" in chess. Depends on your definition of "book moves" Also depends on your definition of "opening" The queens gambit certainly has many book moves.
Even the Ponziani has book moves in one variation of more than 30 for each side.
"book moves" can change every day.
Queen's Gambit Declined: Orthodox, Capablanca System, 10.Bxe7 Qxe7 11.O-O Nxc3 12.Rxc3 e5 13.dxe5 Nxe5 14.Nxe5 Qxe5 15.f4 15 book moves for white 14 for black. Ruy López Opening: Marshall Attack, Modern, Main Line, Spassky Variation 18 book moves each