e5 really depends on what your opponent wants to do.
With a classical e4 e5 Nf3 Nc6 approach, it's easy for your opponent to go into the Italian Game with 3.Bc4. Even the relatively calm Guioco Piano (3...Bc5) can be followed up with Evan's Gambit (4.b4), a very aggressive and tactical opening. You might consider the Petrov in response to 2.Nf3 (2...Nf6), it can lead to some semi-open/closed positions.
The Caro is a lot of work, but would probably be more rewarding.
If you are prepared to spend hours learning the delightful tactics and lines of the Caro-Kann(which i was too lazy to study :D)i would defintly recommend it considering that you might catch alot of players offguard and it provides solid play for black.