I wouldn't deny that if [American] football teams were told "You can have one and only one offensive lineup so decide what its going to be once and for all that will be it", I'm sure they would look at it very carefully and decide what is the optimal offensive lineup (spread, split backfield, wishbone, whatever). (And furthermore imagine they were told that the lineup must be symetrical - no unbalanced lines, 3 WR's to one side etc.)
But that wouldn't mean its preferable to have one and only one lineup.
There is one; it's called the Double Wing formation. It's used in youth level up to high school. As a coach, I like it because it's effective, very hard to stop, easy to teach, and fun for the kids.
affliction is enamoured of my part and i am wedded to calamity...