Sometimes it's possible. I don't have a game in mind, but this a common enough pattern, the king can't come up the board.
In a real game the other pieces are stuck behind pawns and such. Either giving mate if they have a free move, or white is up a lot of material so the queen keeps checking.
Perpetual check used to be listed as one cause for draw - but dropped, sometime on 1960s.
On grounds that perpetual check would eventually cause draw under some different rule - either threefold repetition or no progress in 50 moves.
How?
Threefold repetition, sure.
But 50 moves?
Since only 2 repetitions can appear (3rd of any position would draw under that rule), there must be at least 25 distinct positions for perpetual check, in order to draw under 50 move rule without threefold repetition.
Is there any known perpetual check which did chase through 25 different positions without giving a chance to escape check?