I use Yusupov's system:
Pawn 1
Knight 3
Bishop 3
Rook 4.5
Queen 9
With many types of adjustments specific to the position.
I also value the Bishop pair at an additional .5. But really all of this gives you only a very rough idea of how things are going.
Just looked at this Wikipedia page, and it appears many GM's value the pieces differently than their generic values (Bobby Fischer saying a bishop is 3.25, Kasparov dropping the rooks value from 5 to 4.5, etc.)
What do you guys assign to them? Here's mine:
Pawn: 1
Knight: 3.25
Bishop: 3 (3.5 when in a pair)
Rook: 5
Queen: 10
King: 3