Seems as though there might be a correlation with the level/amount of abstract thinking and one's isolation from social interaction - which ensures that I'll never be a GM. 
Rational madness
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Quoted from:
http://scienceblogs.com/cortex/2007/02/intelligence_and_insanity.php
There are differences between incidences of madness in different fields of employment. These are not necessarily about how stressful the job is (cops, dentists, examples of high stress). Anecdotally, scientists have slightly higher than average levels of madness within the general population; Mathematicians have higher levels than Scientists as a whole; and Logicians have higher levels than mathematicians in general.
Chess grandmasters have high levels of madness at times. There was a psychotic world champion (urinated in public at a match); and the sad case of Bobby Fischer, who saw deeper into Chess than anyone before him. Vladimir Nabokov has an entire novel from the viewpoint of a world champion contender (Luzhin) going mad at the tournament, eventually comitting suicide while believeing this to be a clever sacrifice, strategically. In English: "The Defense." In Russian: "The Luzhin Defense" (a triple pun, including on "Illusion").
The 2006 tale of a great Russian Mathematician (Perelman) solving one of the greatest unsolved problems in Math (the Poincare Conjecture) but refusing the Fields prize (top award in Math) has raised public awareness. Moreso, with a controversial New Yorker article on this, which painted the top Chinese Mathematician as the villain...
Other professions have lower than average incidences of madness. I have heard it said: "a writer doesn't want to be crazy in just one way."