What to play against e4?

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JanDomke
I am struggling to play a good opening when my opponent starts with e4. What is a good answer to it?
Pawnlings

Sicilian, C5. E4, C6, Nf3, Nc6, d4, cxd4, Nxd4, Nf6, etc

BeepBeepImA747
E5?