If lose means really "lose" it.. not a planned sacrifice, and there is no visible compensation possible, it's best to move on.
Why do many people quit after losing their queen?


It depends, I guess, on how much you care about avoiding a loss. If my life is on the line, my motto is, never give up, never say die. If it's a game, not so much.

#176 is that form Queens gambit
that question has already been asked and I replied. do you happen to be a chat bot by any chance?

Because without your queen you have a very small chance of winning so continuing to play is honestly just a waste of time.

They resign because they think the game is lost and don't want to spend more time on the lost game.
Which sometimes is not true. I myself remember being down two rooks and a bishop and finding a back-rank mate .
In my case, I'll resign just because the odds of me getting a win become miniscule, no matter what I think about how they got my Queen, usually, by the way, not because their play was 'awesome' but because I blundered... "Oh no, my Queen!".