Outcome of the game when you lose your queen almost always favors your opponent and will happen 99%. They just resign to not waste time since them losing is more likely than anything else.
I sometimes win despite the loss of a queen and material disadvantage (at least against my app on the phone), so that is no reason to quit.
#137 nope, that would be a stupid thing to do and why would GMs resign then? Resigning simply means realizing game is lost