Would you give up your queen for 3 minor pieces in the middlegame?

3 pieces are worth more than a queen so trading a queen for 3 pieces is good.

I would give up 3 minor pieces for a queen. They are often much better than a queen, but only if they are coordinated. If the minor pieces are undefended, the queen destroys them.
In the example below, black's queen is practically useless, since all of white's pieces are defended. Slowly, white will make progress and win the game.

I watched this just yesterday or the day before yesterday.. Imbalances are quite required parts to cover in endgame practice

https://www.chess.com/lessons/master-material-imbalances

We play Speed Chess mostly so the standard advice might not always apply. When time is running short I find that Queen is more successful at probing for mistakes and more likely to be able to escape with a draw if things aren't looking good.

I would generally not.

"Would you give up your queen for 3 minor pieces..."

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In a standard rated game, I would evaluate carefully before making such informed decisions. More often than not, I would already have been a piece up before exchanging a queen for two minor pieces to yield a net overall of a queen for three pieces, and in that scenario, keeping a piece lead may be more worth it.

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In a casual game, however, I am very inclined to do so. Who says that a queen rules them all?

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The only exception to this is when I am attempting to exchange my queen for three bishops, all residing on the same colour squares.

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nice

watch the first video in the serie, it depends quite a few factors.. king safety first though. video course explains it well

Ceteris Paribus a queen is probably a bit of an underdog against two knights and a bishop. Against two bishops and a knight, the queen is a significant underdog. But positional factors must be taken into account. Are the pieces coordinated. Are there weak pawns around, isolated or linked. Is the king airy or safe.

Q against minor pieces in fast disciplines often has the opposite effect. The queen can be very dangerous with little time on the clock. Just an observation that I have seen several times.

As for pawnless endings:

Two knights normally draw against a queen.

Two bishops normally lose to a queen, although it takes up to 71 moves.
A bishop and knight normally lose to a queen.