I would say this comes down to all the understanding of quantum mechanics, and the absolute randomness this implies. Even ignoring the fact that obtaining any information about the state of a nucleus has a big effect on its state, the maximum amount of information you can obtain only provides limited predictive capability, and this partial predictive information declines towards zero at an extremely high rate after such an observation.
In the usual case where you have a nucleus about which you only have basic information about its state (number of protons and neutrons and say the fact that it is in its ground state), the fact that there is no information you could possess about the nucleus that would provide complete predictability of its decay certainly means that without this information the decay is uncertain.
The actual practical uncertainty is such that a poisson distribution (the canonical probability distribution for a one-off event that has an equal probability of happening in any time interval of a given time.
The correctness of this probability model (by comparison with one where the rate would vary in some way over time) is proven empirically by large numbers of observations.
you are welcome to expend your thoughts about why radiation decay is a truly random process. preferably with your own words. however, if you chose to do so, i want to take this opportunity and encourage you to do so politely. Gracias!