Whats the best way to respond to e4?

I play e5 but have come up against different variations. What's your opinion?

Caro-Kann! is my favourite against e4

Nice

are you talking about my looks or the opening?

Sicialian, French, Caro-Kann, Owen Defense

Keep them coming

Personally, I believe the best way to respond to 1.e4 is to seize your opponent's clock, prop it up right into the exosphere, and lo and behold, time for your opponent's clock will pass faster via the legendary general relativity. Quickly play your move 1.e5 (so you can witness the full effect of the aggravation), before gazing directly at your opponent with a cold, sunken, yet innocuous eye, and fomenting the rage. Psychologically and neuroscientifically proven method that has recently become all the rage in FIDE tournaments, and will no doubt induce the rage. Sign now for your rocket ship, which will casually prop your clock into the exosphere. Auf Wiedersehen!

WOW. Top Marks. @MetaphysiclWukong

there is no hard and fast rule in chess .. just play any move that u a comfortable with... focus on end game thats more important..... opening dont really matter that much

Nice advice

Sicilian Dragon

It's a matter of taste, I recommend french or caro kann, because is more easy to learn

Thx @Cricket334

This is not a defense to 1.e4.  It is a Defense to 1.d4.

To answer the OP, there are 4 responses that are better than the other 16:

Double King Pawn (1...e5)

Sicilian (1...c5)

French (1...e6)

Caro-Kann (1...c6)

Of those 4, there is no best.  Those 4 are better than Black's other 16 legal moves, but of those 4, it is all about personal preference and which you understand (NOT MEMORIZE) best.

Thx prfen

It depends on what you are searching for. 

I'm searching for a toothbrush

Opening Principles:

1. Control the center squares – d4-e4-d5-e5.
2. Develop your minor pieces toward the center – piece activity is the key. Centralized piece control more squares.
3. (King Safety)
4. Connect your rooks. There should be no pieces between your Rooks.

The objective of development is about improving the value of your pieces by increasing the importance of their roles (Piece Activity).  Well-developed pieces have more fire-power than undeveloped pieces and they do more in helping you gain control.

Now we will look at 5 practical things you can do to help you achieve your development objective.

They are:

1. Give priority to your least active pieces.

• Which piece needs to be developed (which piece is the least active)?
• Where should it go (where can its role be maximized)?

2. Exchange your least active pieces for your opponent’s active pieces.
3. Restrict the development of your opponent’s pieces.
4. Neutralize your opponent’s best piece.
5. Secure strong squares for your pieces.

Don’t help your opponent develop.

There are 2 common mistakes whereby you will simply be helping your opponent to develop:

1. Making a weak threat that can easily be blocked
2. Making an exchange that helps your opponent to develop a piece

Gr8 explanation @KetoOn1963

Thank You.

There is no need to worry about move 2 at your level.  Just keep it simple.

If you want to play an unrated game of daily chess let me know.